Located 4.2 km from Museo del Sale, Le Isole Hotel Trapani is about a 5-minute ride from Porta Oscura e Torre Dell'orologio Museum. Public parking is available nearby.

The guest house is about 15 km from Vincenzo Florio airport and 10 minutes by car from such cultural venues as Museo Pepoli. Standing a 5-minute stroll from Cattedrale di San Lorenzo, the hotel is only a few metres from Trapani Cathedral. The accommodation is 10 minutes' drive from Basilica-Santuario Maria SS. Anunziata Di Trapani. San Vito lo Capo Shuttle bus stop is located only a short drive from Le Isole Hotel.

Bathrooms feature a separate toilet and a shower, along with comforts such as hair dryers and towels.

G & G Ristorante is 5 minutes' stroll away and serves Southern-Italian cuisine.